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. 2021 Feb 18;12:639417. doi: 10.3389/fphys.2021.639417

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Copyright © 2021 Badoer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Average number of activated neurons per section in the arcuate nucleus (ARC) and paraventricular nucleus (PVN) in the hypothalamus in control or following administration of leptin or resistin alone or in combination. Modified from Kosari et al. (2012). * represent significantly greater than control. # represents significantly greater than leptin or resistin administered alone. Note that only in the ARC was there a greater number of activated neurons following leptin and resistin combined compared to when each was administered alone.