FIGURE 2.
Results of the GO enrichment and KEGG pathways enrichment analyses. (A,C,E,G) Lollipop plots of GObp, GOmf, GOcc, and KEGG pathways enrichments, respectively. Here, X-axis represents fold enrichment of each of the enriched functional domains derived from enriched GO terms and KEGG pathways. (B,D,F,H) Partial heatmaps showing the number of host targets shared between each of the enriched GObp, GOmf, GOcc, and KEGG pathways. (I) Venn diagram where the blue, green, and purple circles represent GObp, GOmf, and KEGG pathways, respectively. The number within each circle represents the number of multifunctional host targets in the respective functional categories. Five multifunctional proteins were common to three of the functional categories; these were P53, HIF1A, and STAT1. (J) Heatmap showing the aforementioned highly multifunctional host targets and the functions in which they participate.