FIGURE 4.

(A) Circos plot representing the functions or biological processes of protein complexes that are connected by intermodular PPIs targeted by KP. The width of the ribbons within the circus plot represents the number of host targets that mediate the above-mentioned inter-complex interactions, i.e., wider ribbons are indicative of a higher number of host target proteins while narrow ribbons indicate the existence fewer number of host target proteins mediating the given inter-complex interactions. (B) How the FFIN shrinks as we increase the edge weight of the FFIN network. The X-axis here represents the edge weight (measured as the no. of inter-functional connections, i.e., number of inter-complex PPIs) and the Y-axis represents the network size measured as the number of nodes.