Figure 2.

Effect of ginsenoside Rg1 on Aβ1–42 associated protein and pS404-tau expression in AD tree shrews. Immunohistochemical analysis of (A and C) APP, (E and G) Aβ1–42 and (F and H) pS404-tau in the hippocampus and cortex. Western blot analysis of (B and D) BACE1 in the hippocampus and cortex. **P<0.01. Aβ, amyloid β; pS404-tau, tau phosphorylated at serine 404; AD, Alzheimer's disease; APP, amyloid precursor protein; CT, control group; D+A, model group; D+A+Rg1, treatment group; Rg1, ginsenoside Rg1; Hipp, hippocampus; cor, cortex; BACE1, β-secretase 1.