Table 4.
Proteins found to be up- and downregulated in coronary artery disease patients.
| Gene Name | Cardiovascular Disease | Variation | Included/Not Included in the Vesiclepedia |
|---|---|---|---|
| AGT | Coronary artery disease (CAD) | + | Included |
| C4B | Coronary artery disease (CAD) | + | Included |
| HP | Coronary artery disease (CAD) | + | Included |
| FGG | Coronary artery disease (CAD) | + | Included |
| FGB | Coronary artery disease (CAD) | + | Included |
| VIM | Coronary artery disease (CAD) | + | Not included |
| ITIH4 | Coronary artery disease (CAD) | + | Not included |
| C9 | Coronary artery disease (CAD) | + | Not included |
| IGKC | Coronary artery disease (CAD) | + | Not included |
| MYBPC3 | Coronary artery disease (CAD) | + | Not included |
| SERPINA3 | Coronary artery disease (CAD) | + | Not included |
| LRG1 | Coronary artery disease (CAD) | + | Not included |
| CFHR1 | Coronary artery disease (CAD) | + | Not included |
| IGKVA-1 | Coronary artery disease (CAD) | + | Not included |
| PROS1 | Coronary artery disease (CAD) | − | Included |
| C4A | Coronary artery disease (CAD) | − | Included |
| A1BG | Coronary artery disease (CAD) | − | Included |
| KNG1 | Coronary artery disease (CAD) | − | Included |
| CLU | Coronary artery disease (CAD) | − | Included |
| C3 | Coronary artery disease (CAD) | − | Included |
| CD5L | Coronary artery disease (CAD) | − | Included |
| APOL1 | Coronary artery disease (CAD) | − | Included |
| TF | Coronary artery disease (CAD) | − | Included |
| ALB | Coronary artery disease (CAD) | − | Included |
| MBL2 | Coronary artery disease (CAD) | − | Included |
| TTR | Coronary artery disease (CAD) | − | Included |
| SERPINA1 | Coronary artery disease (CAD) | − | Included |
| AFM | Coronary artery disease (CAD) | − | Not included |
| IGFALS | Coronary artery disease (CAD) | − | Not included |
| HPX | Coronary artery disease (CAD) | − | Not included |
| SERPINC1 | Coronary artery disease (CAD) | − | Not included |
| DBP | Coronary artery disease (CAD) | − | Not included |
| CFI | Coronary artery disease (CAD) | − | Not included |
| IGHM | Coronary artery disease (CAD) | − | Not included |
| APOM | Coronary artery disease (CAD) | − | Not included |
| CLEC3B | Coronary artery disease (CAD) | − | Not included |
| PON3 | Coronary artery disease (CAD) | − | Not included |
| SHBG | Coronary artery disease (CAD) | − | Not included |
Legend: CAD, coronary artery disease; AGT, angiotensinogen; C4B, complement C4-B; HP, haptoglobin; FGG, fibrinogen gamma chain; FGB, fibrinogen beta chain; VIM, vimentin; ITIH4, inter-alpha-trypsin inhibitor heavy chain H4; C9, complement component C9; IGKC, immunoglobulin kappa constant; MYBPC3, myosin-binding protein C, cardiac-type; SERPINA3, alpha-1 antichymotrypsin; LRG1, leucine-rich alpha-2-glycoprotein; CFHR1, complement factor H-related protein 1; IGKVA-1, immunoglobulin kappa variable 4-1; PROS1, vitamin K-dependent protein S; C4A, complement C4-A; A1BG, alpha-1B-glycoprotein; KNG1, kininogen-1; CLU, clusterin; C3, complement C3; CD5L, CD5 antigen-like; APOL1, apolipoprotein L1; TF, serotransferrin; ALB, serum albumin; MBL2, mannose-binding protein C; TTR, transthyretin; SERPINA1, alpha-1-antitrypsin; AFM, afamin; IGFALS, insulin-like growth factor-binding protein complex acid labile subunit; HPX, hemopexin; SERPINC1, antithrombin-III; DBP, vitamin D-binding protein; CFI, complement factor I; IGHM, immunoglobulin heavy constant mu; APOM, apoliprotein M; CLEC3B, tetranectin; PON3, serum paraoxonase/lactonase 3; SHBG, sex hormone-binding globulin; +, up-regulated; −, down-regulated.