Table 2.
Varieties in the molecular weight and dosage of hyaluronic acid (HA).
| Brand Name Manufacturer |
Generic Content | Molecular Weight (kDa) | Dosage |
|---|---|---|---|
| Hyalgan (Fidia Pharma) |
1% sodium hyaluronate | 500–730 | 20 mg weekly (five injections) |
| Synvisc (Sanofi) |
0.8% hylan G-F 20 | 6000 | 16 mg weekly (three injections) |
| Synvisc-One (Sanofi) |
0.8% hylan G-F 20 | 6000 | 48 mg one-time injection |
| Supartz (Bioventus) |
1% sodium hyaluronate | 620–1170 | 10 mg weekly (five injections) |
| Euflexxa (Ferring B.V.) |
1% sodium hyaluronate | 2400–3600 | 20 mg weekly (three injections) |
| Gel-One (Zimmer) |
1% cross-linked hyaluronate | Not disclosed | 30 mg one-time injection |
| Orthovisc (DePuy Synthes) |
1.5% sodium hyaluronate | 1000–2900 | 30 mg weekly (three to four injections) |
| Monovisc (Anika/Pendopharm) | 2.2% cross-linked hyaluronan (proprietary cross-linking agent) | 1000–2900 | 88 mg one-time injection |
| GenVisc 850 (Adant) (OrthogenRx) | 1% sodium hyaluronate | 620–1170 | 25 mg weekly (five injections) |
| Hymovis (Fidia Pharma) |
0.8% hexadecylamide derivative of hyaluronan | 500–730 | 24 mg weekly (two injections) |
| Gelsyn-3 (Gel-Syn) (Bioventus LLC) | 0.84% sodium hyaluronate | 1100 | 16.8 mg weekly (three injections) |
| Durolane (Bioventus LLC) |
non-animal stabilized hyaluronic acid |
Not disclosed | 60 mg one-time injection |