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. 2021 Feb 1;6(1):11. doi: 10.3390/geriatrics6010011

Table 3.

Cox Proportional Hazards Regression Analysis: relationships between age, sex, frailty, illness acuity, multimorbidity and death.

Univariable Analysis Multivariable Analysis
Characteristic HR 95% Confidence Interval HR 95% Confidence Interval
Age, years 1.04 1.02, 1.07 1.04 1.01, 1.07
Sex
Women Ref Ref
Men 1.47 0.94, 2.30 2.03 1.27, 3.24
CFS
1–4 Ref Ref
5–6 1.99 1.11, 3.59 1.78 0.90, 3.53
7–8 2.83 1.54, 5.19 2.57 1.26, 5.24
Acuity, NEWS2
Low (<5) Ref Ref
High (≥5) 2.30 1.42, 3.65 2.33 1.45, 3.74
Multimorbidity
0–1 LTC Ref Ref
2 LTC 0.99 0.30, 3.28 0.89 0.22, 2.68
≥3 LTC 1.44 0.58, 3.58 0.85 0.32, 2.30

HR: Hazard Ratio; CFS: Clinical Frailty Scale; NEWS2: National Early Warning Score 2; LTC: long term condition(s). HRs adjusted for all co-variables in multivariable models.