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. 2021 Feb 15;6(8):5075–5090. doi: 10.1021/acsomega.0c05276

Figure 3.

Figure 3

(A) Synthesis of near-infrared fluorescent and reduction-sensitive polypeptide nanogels through N-carboxy-anhydride (NCA) ring-opening polymerization of l-lysine and l-cystine NCA and subsequent conjugation of cyanine dyes. Reprinted with permission from ref (13). Copyright 2012 American Chemical Society. (B) The reversible addition–fragmentation chain transfer polymerization synthesis of random copolymers with pendant pyridyldisulfide groups and the fabrication of biohybrid nanogels demonstrate the structural transition above the lower critical solution temperature. Reprinted with permission from ref (25). Copyright 2016 American Chemical Society.