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. 2021 Mar 4;21:149. doi: 10.1186/s12935-021-01825-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — LINC00470 expression in serum exosomes was negatively correlated with survival of glioma patients. Note: Expression of LINC00470 in HCs’ serum exosomes treated by RNase or RNase + TritonX-100 was detected by qRT-PCR (a). Detection of LINC00470 expression in serum exosomes of glioma patients and HCs by qRT-PCR (b). Kaplan–Meier method was used to examine the correlation of LINC00470 expression in serum exosomes of glioma patients with survival time (c). ** P < 0.01, *** P < 0.001, compared to HC-exo group. # P < 0.05, compared to glioma (grade I ~ II) group. GBM-exo, exosomes derived from patients with glioma; HC, health checker