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. 2021 Feb 17;6(8):5490–5498. doi: 10.1021/acsomega.0c05817

Figure 2.

Figure 2

Dhcr7+/– heterozygosity decreases ARI levels in the liver. Levels of ARI and its metabolites were determined in maternally exposed pups at an age of P0. Samples were grouped taking into account both the maternal and newborn mouse genotypes. WT and Dhcr7+/– pups are depicted in green or red, respectively. ARI (A), D-ARI (B), and 2,3-DCPP (C) were determined using LC–MS/MS. Bars correspond to the mean ± SEM; statistical significance: *p < 0.05; **p < 0.01. A two-way ANOVA analysis is presented in Table 1. Note the lower levels of ARI and D-ARI in Dhcr7+/– pups.