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Febuxostat restored propofol-induced reduction of the transcriptional factor KLF6. Cells were stimulated with 2% propofol in the presence or absence of febuxostat (10, 20 μM) for 24 h. (A) mRNA of KLF6. (B) Expression of KLF6 (####P < 0.0001 vs the vehicle group; **P < 0.01, ***P < 0.001 vs the propofol group, n = 6).
