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Changes in the expression of the Alzheimer's disease-linked genes in the CA1 region of the hippocampus at various times after experimental ischemic brain injury.
 |
APP | BACE1 | PSEN1 | PSEN2 | MAPT |
|---|---|---|---|---|---|
| 2 days | ↓ | ↑ | ↑ | ↑ | ↑ |
| 7 days | ↑ | ↑ | ↑ | ↑ | ↓ |
| 30 days | ↑ | ↓ | ↓ | ↓ | ↓ |
Expression: ↑, increase; ↓, decrease. Genes: APP, amyloid protein precursor; BACE1, β-secretase; PSEN1, presenilin 1; PSEN2, presenilin 2; MAPT, Tau protein.
