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(A,B,C) Representative images of the grading system for pancreatic ductal adenocarcinoma: G1 (A, original magnification 20X), G2 (B, original magnification 20X) and G3 (C, original magnification 20X). D) In the setting of neo-adjuvant therapy, pancreatic ductal adenocarcinoma should not be graded, due to the unreliability of grading for the iatrogenic modifications of tissues, including therapy-induced cell atypia (original magnification 20X).
