Table 1. Cellular t-tubule morphology of control and R6/2 skeletal muscles.
| Transverse element (% pixels) | Longitudinal element (% pixels) | T-tubule density (% pixels) | Axial spacing (μm) | Orthoaxial spacing (μm)b | Regularity (AU) | Integrity (TTint) | |
|---|---|---|---|---|---|---|---|
| Control | 7.26 ± 1.8 | 3.17 ± 1.3 | 10.42 ± 2.42 | 0.94 ± 0.03 | 0.81 ± 0.03 | 0.17 ± 0.1 | 1.8 ± 0.97 |
| R6/2 | 7.04 ± 1.7 | 3.72 ± 1.6 | 10.76 ± 2.02 | 0.94 ± 0.02 | 0.81 ± 0.03 | 0.20 ± 0.1 | 2.0 ± 1.07 |
| P valuea | 0.644 | 0.334 | 0.704 | 0.720 | 0.821 | 0.505 | 0.538 |
Summary of the whole cell t-tubular density in control and R6/2 muscle fibers. Values shown as mean ± SD; n = control (five mice and 13 fibers) and R6/2 (five mice and 13 fibers). AU, arbitrary units; TTint, t-tubule integrity.
a
Mann–Whitney.
b
n = control (seven fibers) and R6/2 (four fibers).