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. 2021 Mar 4;160(7):2435–2450.e34. doi: 10.1053/j.gastro.2021.02.056

Supplementary Table 7.

COVID-19 Disease Severity and Mortality in Patients With and Without GI Symptoms in the Discovery Cohort

GI symptom Severity GI symptom
P valuea
Presence, n Absence, n
Nausea Mild 16 38 .0112
Moderate 102 259
Severe 32 126
Severe EOD 7 54
Vomiting Mild 10 44 .0156
Moderate 56 305
Severe 11 147
Severe EOD 5 56
Diarrhea Mild 26 28 .0102
Moderate 152 209
Severe 52 106
Severe EOD 15 46
Any GI symptoms Mild 31 23 .0003
Moderate 188 173
Severe 63 95
Severe EOD 17 44
Mortality
Nausea Nonsurvivor 21 130 .0003
Survivor 136 347
Vomiting Nonsurvivor 8 143 .0008
Survivor 74 409
Diarrhea Nonsurvivor 39 112 .0002
Survivor 206 277
Any GI symptoms Nonsurvivor 47 104 <.0001
Survivor 252 231
a

Fisher exact test was used to calculate P values.