Table 2.
Laboratory Characteristics of Subjects Without Hemolytic Uremic Syndrome at the Index Emergency Department Visita
| No HUS Following the Index ED Visit (n = 760) |
Developed HUS Following the Index ED Visit (n = 126) |
||||
|---|---|---|---|---|---|
| Characteristic | No. Performed | Median (IQR) | No. Performed | Median (IQR) | P Valueb |
| WBC count, ×103/μL | 484 | 10.6 (8.7–13.2) | 108 | 14.8 (11.8–21.0) | <.001 |
| Hemoglobin, g/dL | 484 | 13.7 (12.6–14.7) | 109 | 14.0 (12.6–15.0) | .28 |
| Hematocrit, % | 483 | 39.7 (37.0–43.0) | 109 | 40.7 (37.2–43.0) | .25 |
| Platelet count, ×103/μL | 481 | 270 (230–329) | 106 | 270 (207–332) | .45 |
| Lactate dehydrogenase, U/L | 41 | 242 (190–293) | 18 | 802 (282–4103) | <.001 |
| Serum sodium, mEq/L | 454 | 138 (136–140) | 103 | 136 (133–138) | <.001 |
| Serum bicarbonate, mEq/L | 422 | 22 (20–24) | 101 | 20.0 (18–23) | <.001 |
| Serum creatinine, mg/dL | 455 | 0.4 (0.3–0.6) | 102 | 0.4 (0.3–0.6) | .71 |
| Blood urea nitrogen, mg/dL | 440 | 9.0 (7.0–12.0) | 101 | 11.0 (8.0–14.3) | <.001 |
| Erythrocyte sedimentation rate, mm/h | 124 | 10 (6–15) | 21 | 8 (6–13) | .22 |
| C-reactive protein, mg/dL | 174 | 2.0 (1.0–5.3) | 35 | 5.6 (1.6–33.3) | .002 |
| Urine protein positive,c No. (%) | 242 | 78 (32.2) | 40 | 19 (47.5) | .07 |
| Urine protein ≥3+ (ie, large), No. (%) | 76 | 8 (10.5) | 17 | 3 (17.6) | .68 |
| Urine blood positived, No. (%) | 231 | 83 (35.5) | 40 | 16 (40.0) | .60 |
| Urine blood ≥3+ (ie, large), No. (%) | 80 | 9 (11.3) | 15 | 5 (33.3) | .04 |
Data are presented as median (IQR) unless otherwise indicated.
Abbreviations: ED, emergency department; HUS, hemolytic uremic syndrome; IQR, interquartile range; WBC, white blood cell.
aTable excludes the 41 children who had HUS at the time of the index ED visit.
b P < .04 was considered statistically significant after P value adjustment via Benjamini-Hochberg procedure for multiple comparisons (n = 15) [27].
c≥1+ protein.
d≥1+ blood.