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. 2021 Mar 4;16(3):e0246265. doi: 10.1371/journal.pone.0246265

Table 7. Histopathological findings in pancreatic tissues of normal rats, diabetic non treated rats and diabetic treated rats with either quercetin, quercetin/Zn, or stem cells separately or in combination.

Findings Control group STZ group STZ plus stem cell group STZ plus (Q) group STZ plus (Q/Zn) group STZ plus (Q) plus stem cells STZ plus (Q/Zn) plus stem cells
Normal pancreatic parenchyma ++++ ------ - - ++ ++++ ++++ ++++ ++++
Detached pancreatic parenchyma ------ ++++ - - ++ ------ ------ ------ ------
Normal sized islets of Langerhans ++++ ------ - - ++ ++++ - - ++ -+++ ++++
Reduced islets of Langerhans ------ ++++ ------ ------ ------ ------ ------
Mild sized islets of Langerhans ------ - - - + -+++ -+++ - - ++ - - - + - - - +
Enlarged size of islet of Langerhans ------ ------ - - - + - - - + - - ++ -+++ ++++

------Absence of the change in the animals of the studied group.

++++ A change was observed in 90% the group.

-+++ A change was observed in 80% the group.

- - ++ A change was observed in 50% of the group.

- - - + A change was observed in 25% of the group.