Table 7. Histopathological findings in pancreatic tissues of normal rats, diabetic non treated rats and diabetic treated rats with either quercetin, quercetin/Zn, or stem cells separately or in combination.
Findings | Control group | STZ group | STZ plus stem cell group | STZ plus (Q) group | STZ plus (Q/Zn) group | STZ plus (Q) plus stem cells | STZ plus (Q/Zn) plus stem cells |
---|---|---|---|---|---|---|---|
Normal pancreatic parenchyma | ++++ | ------ | - - ++ | ++++ | ++++ | ++++ | ++++ |
Detached pancreatic parenchyma | ------ | ++++ | - - ++ | ------ | ------ | ------ | ------ |
Normal sized islets of Langerhans | ++++ | ------ | - - ++ | ++++ | - - ++ | -+++ | ++++ |
Reduced islets of Langerhans | ------ | ++++ | ------ | ------ | ------ | ------ | ------ |
Mild sized islets of Langerhans | ------ | - - - + | -+++ | -+++ | - - ++ | - - - + | - - - + |
Enlarged size of islet of Langerhans | ------ | ------ | - - - + | - - - + | - - ++ | -+++ | ++++ |
------Absence of the change in the animals of the studied group.
++++ A change was observed in 90% the group.
-+++ A change was observed in 80% the group.
- - ++ A change was observed in 50% of the group.
- - - + A change was observed in 25% of the group.