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. 2021 Mar 4;16(3):e0246245. doi: 10.1371/journal.pone.0246245

Table 2. Meibomian gland dysfunction scores before and after treatment.

BL FU1 FU2 p (BL–FU2) p (BL–FU1) p (FU1–FU2)
Group 1
BUT 4.02 ± 1.75 6.02 ± 2.32 7.95 ± 2.54 0.004 0.023 0.002
Oxford Gr 1.42 ± 0.59 0.72 ± 0.65 0.45 ± 0.60 <0.001 <0.001 0.042
MGE 1.97 ± 0.77 1.56 ± 0.69 1.42 ± 0.75 0.001 <0.001 0.388
MQ 2.08 ± 0.61 0.20 ± 0.09 0.17 ± 0.09 <0.001 <0.001 0.645
OSDI 58.86 ± 19.88 41.23 ± 26.46 27.75 ± 11.55 <0.001 0.040 0.002
Group 2
BUT 4.60 ± 1.32 4.86 ± 2.11 7.41 ± 3.37 0.005 0.029 0.007
Oxford Gr 1.50 ± 0.67 0.80 ± 0.76 0.38 ± 0.49 <0.001 <0.001 0.030
MGE 1.93 ± 0.95 1.56 ± 0.79 1.50 ± 0.51 0.032 <0.001 0.333
MQ 2.11 ± 0.50 0.19 ± 0.10 0.19 ± 0.06 <0.001 <0.001 0.333
OSDI 64.92 ± 21.88 39.20 ± 15.42 26.55 ± 13.95 <0.001 <0.001 <0.001

BL = baseline; FU1 (first follow-up) = 2 weeks after the second treatment session; FU2 (second follow-up) = 2 weeks after the fourth treatment session; BUT = tear film break up time; MGE = Meibomian gland expressibility score; MQ = meibum quality score; OSDI = Ocular Surface Disease Index.

p-values were obtained using Wilcoxon signed-rank test.