Table 1. Dose, survival and fever of animals in the Dose ranging Studies.
Animal ID | Dose (cfu) | 1Time to onset of hypothermia (hours) | 2Time to onset of fever (hours) | Duration of fever (hours) |
---|---|---|---|---|
Marmoset 1 | 2.70 x 108 | 61.7 | 32.8 | 28.9 |
Marmoset 2 | 2.70 x 108 | 60.4 | 35.7 | 24.8 |
Marmoset 3 | 1.33 x 102 | n/a | NF | NF |
Marmoset 4 | 1.33 x 102 | n/a | NF | NF |
Marmoset 5 | 1.33 x 104 | n/a | NF | NF |
Marmoset 6 | 1.33 x 104 | n/a | NF | NF |
Marmoset 7 | 6.20 x 105 | 81.4 | 40.5 | 40.9 |
Marmoset 8 | 6.20 x 105 | n/a | NF | NF |
Marmoset 9 | 6.20 x 106 | 68.9 | 42.0 | 26.9 |
Marmoset 10 | 6.20 x 106 | 64.0 | 34.9 | 29.1 |
Marmoset 11 | 6.79 x 105 | n/a | NF | NF |
Marmoset 12 | 6.79 x 105 | n/a | NF | NF |
Marmoset 13 | 6.79 x 106 | 81.6 | 46.3 | 35.3 |
Marmoset 14 | 6.79 x 106 | 61.2 | 38.7 | 22.6 |
1 This time represents a temperature drop to 39°C, following fever, in order to standardise to facilitate comparison between animals.
2fever defined as a temperature of 40°C for at least 3 consequence readings n/a is not applicable as animals survived to the end of the study
NF is no fever observed