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. 2021 Feb 22;15(2):e0009016. doi: 10.1371/journal.pntd.0009016

Table 1. Dose, survival and fever of animals in the Dose ranging Studies.

Animal ID Dose (cfu) 1Time to onset of hypothermia (hours) 2Time to onset of fever (hours) Duration of fever (hours)
Marmoset 1 2.70 x 108 61.7 32.8 28.9
Marmoset 2 2.70 x 108 60.4 35.7 24.8
Marmoset 3 1.33 x 102 n/a NF NF
Marmoset 4 1.33 x 102 n/a NF NF
Marmoset 5 1.33 x 104 n/a NF NF
Marmoset 6 1.33 x 104 n/a NF NF
Marmoset 7 6.20 x 105 81.4 40.5 40.9
Marmoset 8 6.20 x 105 n/a NF NF
Marmoset 9 6.20 x 106 68.9 42.0 26.9
Marmoset 10 6.20 x 106 64.0 34.9 29.1
Marmoset 11 6.79 x 105 n/a NF NF
Marmoset 12 6.79 x 105 n/a NF NF
Marmoset 13 6.79 x 106 81.6 46.3 35.3
Marmoset 14 6.79 x 106 61.2 38.7 22.6

1 This time represents a temperature drop to 39°C, following fever, in order to standardise to facilitate comparison between animals.

2fever defined as a temperature of 40°C for at least 3 consequence readings n/a is not applicable as animals survived to the end of the study

NF is no fever observed