Table 2. Summary of the presence of B. pseudomallei antigen in various marmoset tissues following ingested challenge.
| Animal ID | 12 hour | 36 hour | 48 hour | 54 hour | Terminal | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Stain | H&E | Bps | H&E | Bps | H&E | Bps | H&E | Bps | H&E | Bps | cfu/g |
| Liver | - | - | (1/4) | - | +/- or + (2/4) | - | - | - | ++ (2/4) | - | 2.0 x 107 ± 7.0 x 106 |
| Spleen | - | - | (1/4) | +/- (1/4) | +/- (2/4) | - | - | - | ++ (2/4) | - | 6.5 x 107 ± 5.9 x 107 |
| Kidney | - | - | - | - | - | - | - | - | - | +/- (2/4) | 2.3 x 105 ± 8.3 x 104 |
| Lung | - | - | - | - | - | - | - | - | - | +/++ (2/4) | 1.5 x 106 ± 7.6 x 105 |
| Adrenal Gland | - | - | - | - | - | - | - | - | - | - | N/D |
| Inguinal LN | - | - | - | - | - | - | - | - | N/A | - | N/D |
| Oesophagus | - | - | - | - | - | - | - | - | - | - | N/D |
| Parotid | - | - | - | - | - | - | - | - | - | - | N/D |
| Stomach | - | - | - | - | - | - | - | - | - | - | 1.2 x 106 ± 1.0 x 104 |
| Duodenum | - | - | - | - | - | - | - | - | ++ (1/4) | ++ (1/4) | 2.9 x 107 ± 2.0 x 107 |
| Pancreas | - | - | - | - | - | - | - | - | - | - | N/D |
| Jejunum | - | - | - | - | - | - | - | - | ++ (1/4) | - | 8.9 x 106 ± 3.3 x 106 |
| Ileum | - | - | - | - | - | - | - | - | - | - | 1.2 x 105 ± 7.4 x 104 |
| Caecum | - | - | - | - | - | - | - | - | - | - | 1.4 x 106 ± 7.4 x 105 |
| Colon | - | - | - | - | - | - | + (1/4) | - | - | - | 7.0 x 105 ± 3.2 x 105 |
| Mesenteric LN | - | - | +/++(2/4) | ++(1/4) | - | - | +/++(2/4) | +++(1/4) | ++ (1/4) | +/+++ (2/4) | N/D |
- no lesions/immunological staining
+/- minimal lesions/immunological staining
+ mild lesions/immunological staining
++ moderate lesions/immunological staining
+++ severe lesions/immunological staining
N/D not determined