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. 2021 Feb 19;10:e63524. doi: 10.7554/eLife.63524

Figure 7. A working transport model.

For simplicity, the extracellular domains and the substrate-binding proteins are omitted from the schematic drawings.

Figure 7.

Figure 7—figure supplement 1. Structural comparison of ABCA4 and ABCA1.

Figure 7—figure supplement 1.

(A) The overall structure of ABCA1 in the substrate-free, ATP-free (apo) conformation. (B) The overall structure of ABCA1 in its apo-form. (C) Local superposition of the exocytoplasmic domains (ECDs), transmembrane domains (TMDs), and nucleotide binding domain (NBD)/regulatory domain (RD).