TABLE 2:
Associations of DWI Lesion Features With Patient and Imaging Characteristics in 24 Women With Mammographically Occult Breast Cancer
| Variable | No. of Patients | Conspicuity Scorea | pb | CNRa | pb | ADCa (× 10−3 mm2/s) | pb |
|---|---|---|---|---|---|---|---|
| Overall | 24 | 4 (1-5) | 1.4 (−0.6 to 4.6) | 1.31 (0.49–2.24) | |||
| Age (y) | 0.40 | 0.82 | 0.86 | ||||
| <50 | 11 | 3.5 (1.5–4) | 1.2 (−0.6 to 4.6) | 1.26 (0.62–1.59) | |||
| ≥50 | 13 | 4 (1–5) | 1.6 (−0.4 to 2.8) | 1.35 (0.49–2.24) | |||
| Menopausal status | 0.27 | 0.84 | 0.50 | ||||
| Premenopausal | 10 | 3.5 (1.5–4) | 1.3 (−0.6 to 4.6) | 1.45 (0.74–1.77) | |||
| Postmenopausal | 14 | 4 (1-5) | 1.6 (−0.4 to 4.4) | 1.26 (0.49–2.24) | |||
| Lesion size (mm) | 0.17 | 0.95 | 0.49 | ||||
| ≤10 | 13 | 3.5 (1–5) | 1.2 (0.5–4.6) | 1.45 (0.49–1.77) | |||
| >10 | 11 | 4 (1.5–5) | 1.4 (−0.6 to 4.4) | 1.25 (0.62–2.24) | |||
| Lesion type | 0.12 | 0.67 | 0.72 | ||||
| Mass | 19 | 4 (1–5) | 1.4 (−0.6 to 4.6) | 1.42 (0.49–1.77) | |||
| Nonmass enhancement | 5 | 2.5 (1.5–4) | 1.3 (−0.4 to 1.9) | 1.25(0.83–2.24) | |||
| Histology | 0.25 | 0.44 | 0.88 | ||||
| IDC | 10 | 4 (1–5) | 1.1 (−0.6 to 4.6) | 1.36 (0.49–1.59) | |||
| ILC | 5 | 4 (1.5–4) | 2.5 (0.8–4.4) | 1.08 (0.62–1.51) | |||
| Phyllodes tumor | 1 | 5 | 1.8 | 1.62 | |||
| DCIS | 8 | 2.8 (1.5–4) | 1.3 (−0.4 to 1.9) | 1.30 (0.74–2.24) | |||
| Protocol | 0.38 | 0.17 | 0.93 | ||||
| 1.5 T | 10 | 3.5 (1.5–4) | 1.2 (−0.6 to 2.1) | 1.37 (0.49–1.77) | |||
| 3 T | 14 | 4 (1–5) | 1.9 (−0.4 to 4.6) | 1.31 (0.62–2.24) | |||
Note—IDC = invasive ductal carcinoma, ILC = invasive lobular carcinoma, DCIS = ductal carcinoma in situ.
a
Median (range).
b
The p values were calculated using the Mann-Whitney U test; histology comparisons were performed for invasive tumors (i.e., IDC, ILC, malignant phyllodes tumor) versus noninvasive tumors (i.e., DCIS).