TABLE 3:
Performance of Blinded Readers Using Unenhanced MRI Screening Studies With DWI for Assessing 95 Breastsa of 48 Womenb
| Reader | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|
| Reader 1 | 42 (10/24) | 90 (64/71) | 59 (10/17) | 82 (64/78) | 78 (74/95) |
| Reader 2 | 54 (13/24) | 93 (66/71) | 72 (13/18) | 86 (66/77) | 83 (79/95) |
| Reader 3 | 38 (9/24) | 90 (64/71) | 56 (9/16) | 81 (64/79) | 77 (73/95) |
| Mean reader performance | 45 | 91 | 62 | 83 | 79 |
Note—Raw data (no. /total no.) are presented in parentheses. PPV = positive predictive value, NPV = negative predictive value.
a
Only one breast of one patient was included in the analysis because she had non–mammographically occult disease in the contralateral breast.
b
Twenty-four women with breast cancer and 24 control subjects who were matched 1:1 with the patients with breast cancer for age, breast density, and MRI protocol.