Skip to main content
. Author manuscript; available in PMC: 2022 Feb 10.
Published in final edited form as: Annu Rev Physiol. 2020 Oct 21;83:205–230. doi: 10.1146/annurev-physiol-031220-095215

Figure 3.

Figure 3

Cellular and circuit mechanisms of temperature sensation in Drosophila and C. elegans. (a) Larval and adult flies use different temperature-sensitive neurons for temperature sensation (130). (b) The neural circuit of temperature sensation in adult flies (131, 132). (c) In C. elegans, the AFD neuron is the primary warmth-sensing neuron. Meanwhile, the head neuron ASER and the intestine are cold sensitive through the cold sensors GLR-3 and TRPA-1, respectively. The other head neuron IL1 senses cooling through TRPA-1. (d) The neural circuit of thermotaxis in C. elegans. Abbreviations: IR, ionotropic receptor; LN, local neuron; md, multiple dendritic; PN, projection neuron.