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. 2021 Feb 18;23(2):e23936. doi: 10.2196/23936

Table 7.

Effect of time of day on momentary alertness and cognitive throughput.a

Feature Effect on alertness P value Effect on cognitive throughput P value
Time of day Alertness varies sinusoidally with time of day, with an acrophase at 10:24 (09:26 to 11:21) <.001 Cognitive throughput varies sinusoidally with time of day, with an acrophase at 09:19 (08:13 to 10:26) <.001
Internal time Alertness varies sinusoidally with internal time, with an acrophase at 14:24 (13:20 to 15:31) <.001 Cognitive throughput varies sinusoidally with internal time, with an acrophase at 13:20 (12:02 to 14:38) <.001

aThe acrophase of the 24-hour circadian rhythm of cognitive performance is reported in hh:mm format with the corresponding 95% confidence intervals and P values.