Table 2.
Dxys for the different scoring systems and outcomes presented for t- and p-MDS (therapy-related and primary myelodysplastic syndromes): FAB (French-American-British classification), WHO (World Health Organization classification), IPSS-R (International Prognostic Scoring System-revised), WPSS-R (WHO-based Prognostic Scoring System-revised, cipssr (cytogenetic component of the IPSS-R), number of aberrations, and primary diagnosis.
Score | Transformation free survival | Overall survival | Time to AML | |||
---|---|---|---|---|---|---|
t-MDS | p-MDS | t-MDS | p-MDS | t-MDS | p-MDS | |
FAB | 0.19 | 0.30 | 0.17 | 0.28 | 0.24 | 0.42 |
WHO | 0.24 | 0.29 | 0.19 | 0.26 | 0.41 | 0.44 |
IPSS-R | 0.37 | 0.41 | 0.38 | 0.40 | 0.36 | 0.53 |
WPSS-R | 0.35 | 0.38 | 0.33 | 0.36 | 0.40 | 0.51 |
cipssr | 0.30 | 0.23 | 0.32 | 0.23 | 0.23 | 0.28 |
Number of aberrations | 0.29 | 0.13 | 0.32 | 0.13 | 0.22 | 0.14 |
Primary diagnosis | 0.05 | / | 0.05 | / | 0.03 | / |