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. 2021 Feb 2;40(9):1721–1736. doi: 10.1038/s41388-021-01659-y

Fig. 6. Anti-angiogenic therapy is effective in ERO1-devoid breast tumors.

Fig. 6

A Bioluminescence signals of primary breast tumors and lungs from representative mice orthotopically-injected with WT and ERO1 KO MDA-MB231m, and treated three times with the anti-VEGF, B20 or vehicle. B Bioluminescence signals of ex vivo lungs. C Primary breast tER stress response mediator induced by hypoxia. Its lack impairsumor and (D) lymph node growth. E Dot plots on a logarithmic scale of the bioluminescence counts of lungs after B20 or vehicle treatment.