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. 2021 Feb 19;12:589948. doi: 10.3389/fmicb.2021.589948

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Copyright © 2021 Coclet, Garnier, D’Onofrio, Durrieu, Pasero, Le Poupon, Omanović, Mullot, Misson and Briand.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bar graph representing relative proportions of significant KEGG Pathways at level 3 of SEED metabolic hierarchy in biofilms from contaminated (6ext; red) and uncontaminated (41p; green) sites (A), and in biofilms from surface (yellow) and bottom (blue) (B). Extended error bar plots showed pairwise comparison of significant KEGG Pathway proportions (Welch’s t-test; p < 0.01) at level 3 of SEED metabolic hierarchy between biofilms from contaminated (6ext; red) and uncontaminated (41p; green) sites (A), and between biofilms from surface (yellow) and bottom (blue) (B). Corrected p-value is determined using Fisher’s exact test.