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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Cancer Discov. 2020 Dec 2;11(3):591–598. doi: 10.1158/2159-8290.CD-20-1165

Fig 2: Somatic genome analysis of lung cancers from Mexico and Colombia.

Fig 2:

Co-mutation plot displays alterations in known activators of the RTK/RAS/RAF pathway, tumor suppressor genes and significantly amplified genes. * indicates that oncogenic mutations in EGFR and KRAS as well as truncating mutations in STK11 are associated with NAT ancestry, but other somatic alterations are not; correlations with mutations are controlled for TMB. LATAM: Latin American. The mutation frequency for EUR LUAD is obtained from the TCGA dataset(51). The mutation frequency for EAS LUAD is obtained from Chen et al 2020(12).