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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Cancer Discov. 2020 Dec 2;11(3):591–598. doi: 10.1158/2159-8290.CD-20-1165

Fig 4: Germline local ancestry in association with somatic EGFR and KRAS mutations.

Fig 4:

A) Genome-wide association of local NAT ancestry with EGFR (left) and KRAS (right). “NAT ancestry high” indicates positive association, whereas “NAT ancestry low” indicates negative association. Red line indicates P=0.05. Orange line indicates genome-wide significance threshold (P<5x10−5). B) Association of local ancestry risk score with somatic EGFR or KRAS mutations, controlling for global ancestry (proportion of overall NAT ancestry).