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. 2021 Mar 4;11:156. doi: 10.1038/s41398-021-01204-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Overview of glass brain section showing 3D rendering and B close up of 3D renders of all amygdala nuclei from an example participant. Plots of the a priori amygdala regions, comprising C total amygdala in greyscale, D basolateral nuclei in pink, and E central nuclei in purple containing individual data points and the probability density of the data stratified by group and sex (the group average of the estimated marginal means predicted by the models are indicated by the solid black line, with dotted lines indicating the standard error of the marginal means). The bottom panel shows regression plots for volume of the F total amygdala, G basolateral nuclei, and H central nuclei by alcohol use (standard alcohol drinks per month) in male and female alcohol-dependent participants, adjusted for intracranial volume, age, and education. Only the association in the male group for the total and basolateral amygdala remained significant after FDR correction. The left and right hemispheres for the nuclei have been collapsed. **p(FDR) < 05.