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. 2021 Mar 4;11:5156. doi: 10.1038/s41598-021-84616-9

Figure 2.

Figure 2

Quantification pipeline: a combination of 23Na and 1H imaging modalities are employed to isolate the intracellular component of the total sodium signal. From left to right: four GRE images with incremental TE’s, a 23Na FLORET image and two 1H T1 measurements (pre and post contrast) are independently elaborated to generate, respectively, WF, TSC and ECV. Ultimately, these three maps are combined (Eq. 1) to calculate CIC and ICV.