Figure 5.

Quantitative maps in a post-menopausal 51-years-old patient with triple negative breast cancer (Patient 1) and in a post-menopausal 58-years-old patient with triple negative breast cancer (Patient 2). In patient 1: average ECV and ICV in the lesion were respectively $0.28\pm 0.12$ and $0.55\pm 0.15.$ TSC in the lesion was 47.0 ± 11.1 mM, which was approximately double the TSC measured in contralateral healthy glandular tissue ($23.0\pm 7.6$ mM, not visible in the figure) in accordance with previous findings. ${\text{C}}_{\text{IC}}$ in the lesion was $29.6\pm 17.9$ mM. In patient 2: average ECV and ICV in the lesion were respectively $0.14\pm 0.05$ and 0.69 ± 0.10. TSC in the lesion was $39.2\pm 15.2$ mM, which was three times higher than in contralateral healthy tissue ($13.5\pm 7.5$ mM). ${\text{C}}_{\text{IC}}$ in the lesion was $27.2\pm 21.1$ mM. ECV, extracellular volume fraction; ISC, intracellular volume fraction; TSC, total sodium concentration; ${\text{C}}_{\text{IC}}$, intracellular sodium concentration.