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. 2021 Feb 19;9:604038. doi: 10.3389/fcell.2021.604038

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Copyright © 2021 Pan, Abdureyim, Yao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PRKAA2 expression increased with miR-124-3p knockdown in endothelial cells adhered by PC-3M. (A) The expression level of miR-124-3p in endothelial cells under fluorescence microscope by green fluorescence protein. BF, bright field; GFP, green-fluorescent protein; NC-miR-124-3p: negative control of lentiviral vector; miR-124-3p-down: miR-124-3p knockdown with lentiviral vector. (B) qPCR analysis of relative expression levels of PRKAA2 in HUVECs transfected with LV-miR-124-3p-down. The results show that the expression level of PRKAA2 mRNA in endothelial cells adhered by PC-3M increased greatly with the knockdown of miR-124-3p.