Table 2.
Subject characteristics and iron-related parameters in men and women with obesity.
| Men (n=19) | Women (n=43) | p-value | |
|---|---|---|---|
| Age (years) | 31 ± 6 | 30 ± 7 | 0.87 |
| Body mass index (kg/m2) | 34 ± 3 | 34 ± 3 | 0.46 |
| Body Fat (%) | 37 ± 3 | 46 ± 4 | 2E−12* |
| Plasma [Ferritin] (ng/mL) | 135 ± 88 | 24 ± 21 | 3E−14* |
| Plasma [Hepcidin] (ng/mL) | 45 ± 25 | 23 ± 15 | 7E−5* |
| Hemoglobin concentration (g/dL)a | 14.6 ± 0.7 | 12.4 ± 1.3 | 1E−6* |
| Hematocrit (%)a | 43 ± 3 | 38 ± 3 | 1E−5* |
| Plasma [CRP] (mg/dL) | 0.4 ± 0.3 | 1.0 ± 1.0 | 0.01* |
| Plasma [IL-6] (pg/ml) | 2.7 ± 2.0 | 3.6 ± 3 | 0.09 |
| Liver R2* (Hz)b | 58 ± 10 | 43 ± 9 | 7E−6* |
| Muscle Ferritin Protein Abundance (AU) | 2.2 ± 1.2 | 1.0 ± 0.8 | 1E−4* |
| Muscle Tfrc Protein Abundance (AU) | 0.6 ± 0.2 | 1.5 ± 0.7 | 7E−10* |
Data are presented as mean ± SD.
*
p≤0.01.
a
Hemoglobin concentration and hematocrit were not obtained from 6 men and 8 women so n=13 men and n=32 women for these parameters.
b
MRI scans were not obtained on 2 men and 8 women so liver R2* sample sizes were n=17 men and n= 35 women. BMI, body mass index; CRP: C-reactive protein; Tfrc, transferrin receptor.