Table 1.
Patient characteristics and outcome from 6 [99mTc]Tc-PSMA-I&S RGS lymphadenectomies
| No | Age at surgery (years) | PSA at surgery (ng/ml) | Gleason score at primary stage | Activity 99mTc-PSMA (MBq) | LN/LNM removed overall (n) | LNM detected (n) | Removed non nodal** PCa-tissue (n) | Anatomical subregions at LA (n) | Manually separated “single-samples” (n) |
|---|---|---|---|---|---|---|---|---|---|
| Number of patients (extended lymph node dissections) overall n = 6 | |||||||||
| 1 | 69 | 2.27 | 4 + 3 | 680 | 79 | 15 | – | 18 | 78 |
| 2 | 49 | 128 | 5 + 4 | 660 | 135 | 42 | 1 | 12 | 84 |
| 3 | 63 | 67.63 | 4 + 4 | 692 | 123 | 8 | – | 15 | 126 |
| 4 | 68 | 0.99 | 4 + 4 | 537 | 36 | 2 | – | 8 | 56 |
| 5 | 65 | 11.78 | 4 + 4 | 674 | 50 | 8 | – | 12 | 58 |
| 6 | 52 | 54.82 | 4 + 3 | 584 | 93 | 85 | 10 | 8 | 96 |
| Sum | 516 | 160 | 11 | 73 | 498 | ||||
| Origin of tissue specimens from 73 subregions: n/73 (%) | ||
|---|---|---|
| Right common iliac 7/73 (10%) | Left common iliac 6/73 (8%) | Aortic bifurcation 1/73 (1%) |
| Right external iliac 6/73 (8%) | Left external iliac 7/73 (10%) | Interaortocaval 3/73 (4%) |
| Right obturator iliac 4/73 (6%) | Left obturator iliac 4/73 (6%) | Paraaortal 4/73 (5%) |
| Right internal iliac 7/73 (10%) | Left internal iliac 5/73 (8%) | Miscellaneous* 9/73 (11%) |
| Right presacral region 6/73 (8%) | Left presacral region 4/73 (5%) | |
LNM lymph node metastases, LN lymph node, PSA prostate specific antigen, LA lymphadenectomy, PCa prostate cancer
*miscellaneous regions: mesorectal, pillar of urinary bladder, region of the musculus piriformis, retroduodenal, renal hilum, ductus deferens
**non-nodal PCa-tissue: residuals of seminal vesicle (n = 7), and deferent duct (n = 3) and solid PCa-tissue in the of left fossa obturatoria (n = 1)