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. 2021 Mar 4;11(3):50. doi: 10.1038/s41408-021-00444-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — MGUS monoclonal gammopathy of undetermined significance, MM multiple myeloma, AL immunoglobulin light chain amyloidosis, WM Waldenstrom’s macroglobulinemia, SMM smoldering multiple myeloma, Cryo cryoglobulinemia, LPD-IGM MG lymphoproliferative disorder with monoclonal gammopathy, SWM smoldering Waldenstrom’s macroglobulinemia, PC plasmacytoma, MIDD monoclonal immunoglobulin deposition disease, and CAD cold agglutinin disease. Note that non-glycosylated kappa and lambda light chains (LC) are not mutually exclusive due to bi and triclonality. However, glycosylated LC are mutually exclusive, as LC isotype is in reference to the glycosylated LC, and no patients had glycosylated LC of different isotypes.