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. 2021 Mar 4;11:5265. doi: 10.1038/s41598-021-83894-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Real-time Intra-vital recording of MSC accumulation in the murine lung microvasculature allowed for measurements of velocity in healthy (A) and E. coli infected lung (B). Velocities of individual MSCs (movement indicated by red arrows, A, B, Panels ii–v) were measured in different pulmonary vessel diameters (Blue arrows, A,B, Panel i) Quantitative analysis showed that there was no significant differences in MSC velocities in different vessel diameters between healthy and pneumonia mouse models (C). MSC: Mesenchymal Stem Cell; Columns represent mean + SD (n = 4–13 from 6 separate animals).