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. 2021 Feb 19;15:636707. doi: 10.3389/fncel.2021.636707

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Copyright © 2021 Heyburn, Abutarboush, Goodrich, Urioste, Batuure, Wheel, Wilder, Arun, Ahlers, Long and Sajja.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alterations in neurodegeneration-related proteins following repeated low-level BOP exposure. (A,B) Aβ40 and Aβ42 were significantly reduced in the brain following 14 exposures to 8.5 psi overpressure. (C,D) Representative Western blot image of Aβ40, Aβ42, and β-actin. (E) TDP-43 was trending to increase in the brain following repeated low-level BOP exposure. (F) Representative Western blot image of TDP-43 and β-actin. (G) Phospho-S396 Tau was significantly reduced following 14 exposures to 10 psi overpressure. (H) Representative Western blot images of pTau and β-actin. *p < 0.05, **p < 0.01, ***p < 0.001.