. Author manuscript; available in PMC: 2021 Sep 1.

Published in final edited form as: Pharmacoepidemiol Drug Saf. 2020 Jun 17;29(9):1175–1182. doi: 10.1002/pds.5036

Table 2:

Medication use and risk of clinically-detected atrial fibrillation in longitudinal analyses

Opioid use		Gabapentinoid use		NSAID use
Unadjusted HR (95%CI)	Adjusted HR^a (95%CI)	Unadjusted HR (95%CI)	Adjusted HR^a (95%CI)	Unadjusted HR (95%CI)	Adjusted HR^a (95%CI)
1.33 (1.00, 1.76)	1.17 (0.88, 1.56)	1.28 (0.83, 1.97)	1.06 (0.69, 1.64)	0.90 (0.75–1.09)	1.07 (0.89–1.30)

Adjusted for: age, sex, site, race, height, weight, diabetes, treated hypertension, systolic blood pressure, smoking, alcohol use.

Abbreviations: NSAID, non-steroidal anti-inflammatory drug; HR, hazard ratio; CI, confidence interval.