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. 2021 Feb 19;12:630791. doi: 10.3389/fimmu.2021.630791

Table 1.

The demographic characteristics of the study population.

Characteristics HC (n = 40) AS (pre-treatment) (n = 32) AS (post-treatment) (n = 32) p
Male, n (%) 37 (92.5) 29 (90.6) 1.000*
Age, year, mean ± SD 27.05 ± 5.64 28.63 ± 7.53 0.314*
HLA-B27 positive, n (%) 30 (93.8)
Duration, month, mean ± SD 94.28 ± 48.79
BASDAI, mean ± SD 6.85 ± 2.03 3.28 ± 1.70 <0.001
BASFI, mean ± SD 4.46 ± 2.22 2.37 ± 2.01 <0.001
ASDAS-CRP, mean ± SD 4.36 ± 0.79 1.07 ± 0.73 <0.001
ESR, mm/H, median (IQR) 29.5 (12.5–46.5) 5.0 (3.0–10.8) <0.001
CRP, mg/L, median (IQR) 21.1 (12.4–44.0) 2.6 (1.1–9.5) <0.001

*P-values were calculated with HCs as references. Other p-values were calculated from the comparison between pre- and post-treatment. HC, health control; AS, ankylosing spondylitis; SD, standard deviation; BASDAI, Bath Ankylosing Spondylitis Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; ASDAS, Ankylosing Spondylitis Disease Activity Score; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IQR, interquartile range.