Table 1.
Demographics and clinical characteristics of HD patients and healthy controls.
| HD group | Healthy control group | p value | |
|---|---|---|---|
| N | 33 | 33 | NA |
| M:F | 15:18 | 15:18 | NA |
| Age (y/o) | 42.6 (12.7)a | 48.0 (13.5)a | 0.0967* |
| BMI (kg/m2) | 21.3 (3.7)a | 24.0 (3.6)a | 0.003* |
| HD duration(y) | 4.0 (7.0)b | NA | NA |
| CAG repeat number | 42.0 (3.5)b | NA | NA |
| UHDRS-M | 35.0 (70.0)b | NA | NA |
| FAS scores | 21.0 (11.0)b | NA | NA |
| TFC scores | 12.0 (10.0)b | NA | NA |
| SIT scores | 18.0 (16.0)b | – | NA |
| SDMT scores | 21.0 (25.0)b | – | NA |
| CFT scores | 11.0 (11.0)b | – | NA |
| BDI-II scores | 6.0 (15.0)b | – | NA |
| MMSE scores | 28.0 (5.0)b | – | NA |
*Unpaired t-test; the data are presented as the mean (SD)a or median (IQR)b; HD, Huntington’s disease; NA, not applicable; SD, standard deviation; IQR, interquartile range; M:F, male: female; y, years; y/o, years old; BMI, body mass index; UHDRS-M, motor section of Unified Huntington’s Disease Rating Scale; FAS, Functional Assessment Scale; TFC, Total Functional Capacity; SIT, Stroop Interference Test; SDMT, Symbol Digit Modalities Test; CFT, Category Fluency Test; BDI-II, Beck Depression Inventory II; MMSE, Mini-Mental State Examination.