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. 2021 Feb 19;8:635671. doi: 10.3389/fvets.2021.635671

Table 1.

Clinical signs and outcomes of animals following experimental infection.

Goat ID Onset of clinical signs Clinical signs at onset Clinical signs at advanced stage Outcome
Infected (n = 8)
1 5 dpi Ocular and oronasal secretion, fever (40°C) - Sacrificed at 5 dpi
2 5 dpi Mild watery ocular and oronasal secretion, fever (40°C), mild dullness Moderate oronasal and ocular secretion, fever (40°C), mild to moderate dullness and depression, mild anorexia Sacrificed at 7 dpi
3 6 dpi Ocular secretion, fever (40°C) Moderate oronasal and ocular secretion fever (40.5°C), moderate dullness, anorexia Sacrificed at 10 dpi
4 5 dpi Mild ocular and oronasal secretion, fever (40°C), mild dullness Profuse mucoid oronasal and ocular secretion, high fever (41°C), severe dyspnea, huge diarrhea, anorexia Died at 13 dpi
5 7 dpi Ocular and oronasal secretion, fever (40°C), mild dullness Profuse oronasal and ocular secretion, high fever (41°C), severe dyspnea, diarrhea, anorexia Sacrificed at 14 dpi
6 6 dpi Mild ocular secretion, fever (40°C). Profuse mucoid oronasal and ocular secretion, high fever (41°C), severe dyspnea, diarrhea, anorexia, subnormal temperature before death Died at 15 dpi
7 7 dpi Ocular and oronasal secretion, fever (40°C), mild dullness Profuse oronasal and ocular secretion, high fever (41°C), severe dyspnea, diarrhea, anorexia, subnormal temperature before death Died at 18 dpi
8 8 dpi Ocular and oronasal secretion, fever (40°C) Profuse mucoid oronasal and ocular secretion, high fever (41°C), severe dyspnea and diarrhea, diarrhea subsided after 16 dpi. Sacrificed at 18 dpi
Control (n = 4)
9 - No clinical signs No clinical signs Sacrificed at 5 dpi
10 - No clinical signs No clinical signs Sacrificed at 7 dpi
11 - No clinical signs No clinical signs Sacrificed at 14 dpi
12 - No clinical signs No clinical signs Sacrificed at 18 dpi