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. 2021 Feb 19;12:641917. doi: 10.3389/fphar.2021.641917

FIGURE 5.

FIGURE 5

Western blotting analysis for the expression of p53, caspase9, caspase3, cleaved caspase3, Bax, Beclin-2 (A, B) Compared to the control group, METH significantly increased the expression level of p53, caspase9, caspase3, cleaved caspase3, Bax, and the normalized ratio of Bax/Beclin-2. These alterations were eliminated by luteolin pretreatment. *p < 0.05, **p < 0.01, compared with control group, # p < 0.05, compared with METH group (mean ± SEM).