Table 1.
Correlation between Dkk2 expression and clinicopathologic characteristics of ovarian cancer patients.
| Characteristics | Total | Dkk2 low expression | Dkk2 high expression | P value | |
|---|---|---|---|---|---|
| Number of cases(%) | Number of cases | Number of cases | |||
| Age(y) | |||||
| ≥60y | 73 (46.8) | 28 | 21 | <0.001 | |
| <60y | 83 (53.2) | 17 | 38 | ||
| Tumor histology | |||||
| LGSC | 24 (15.4) | 2 | 17 | 0.001 | |
| HGSC | 80 (51.3) | 28 | 27 | ||
| Clear cell | 12 (7.7) | 0 | 6 | ||
| Endometrioid | 21 (13.5) | 7 | 4 | ||
| Mucinous | 13 (8.3) | 6 | 2 | ||
| Missing | 6 (3.8) | ||||
| FIGO | |||||
| I | 35 (22.4) | 8 | 14 | 0.615 | |
| II | 10 (6,4) | 2 | 4 | ||
| III | 103 (66.0) | 33 | 39 | ||
| IV | 3 (1.9) | 1 | 0 | ||
| Missing | 5 (3.2) | ||||
| Expression of GPER | |||||
| low expression (IRS ≤ 8) | 83 (53.2) | 33 | 28 | 0.005 | |
| high expression (IRS>8) | 70 (44.9) | 11 | 31 | ||
Dkk2, Dickkopf2; GPER, G protein-coupled estrogen receptor; HGSC, high-grade serous carcinoma; LGSC, low-grade serous carcinoma; FIGO, International Federation of Gynecology and Obstetrics.
Bold numbers represent p-values < 0.05.