Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 19;10:610513. doi: 10.3389/fonc.2020.610513

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Gao, Huang, Wang, Pan, Yin, Zhou and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Classification based on tumor microenvironment stratifies HCCs into four subclasses. (A) Correlation heatmap of 11 TME cell signatures in two data sets. Color scale: Spearman correlation coefficient from 0 (blue) to 1 (orange). (B) Consensus clustering analysis of two data sets revealed four HCC subclasses based on 13 TME signatures. Color scale: Z score from -2 (blue) to +2 (orange). (C) Principal-component analysis based on 13 TME signatures separated different subclasses in TCGA cohort. Kaplan-Meier curves of overall survival for TCGA cohort (D) and CHCC-HBV cohort (E) based on immune subclasses (log-rank test).