Table 2.
Logistic Regression Analysis: Associations Between Clinical Profiles and Non-Home Discharge
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Demographic data | ||||||
| Age (per 1-year increase) | 1.06 | 1.00–1.12 | 0.055 | |||
| Female sex | 1.13 | 0.61–2.09 | 0.71 | |||
| BMI (per 1-kg/m2 increase) | 0.95 | 0.88–1.02 | 0.17 | |||
| NYHA III or IV | 3.25 | 1.71–6.17 | <0.001 | |||
| 5-m walking time (per 1-s increase) | 1.03 | 0.98–1.10 | 0.26 | |||
| Hand-grip strength (per 1-kg increase) | 0.97 | 0.92–1.01 | 0.15 | |||
| HDS-R (per 1-point increase) | 0.95 | 0.90–1.00 | 0.049 | 0.98 | 0.92–1.06 | 0.63 |
| Past medical history | ||||||
| Hypertension | 0.50 | 0.28–0.88 | 0.017 | 0.59 | 0.27–1.30 | 0.19 |
| Diabetes | 1.09 | 0.56–2.12 | 0.80 | |||
| Peripheral artery disease | 2.96 | 1.60–5.48 | 0.001 | 2.73 | 1.25–5.97 | 0.012 |
| Previous stroke | 3.30 | 1.71–6.39 | <0.001 | 2.57 | 1.03–6.45 | 0.044 |
| AF/AFL | 1.86 | 1.05–3.41 | 0.033 | 1.18 | 0.56–2.49 | 0.67 |
| COPD | 1.68 | 0.49–5.77 | 0.41 | |||
| OMI | 0.61 | 0.14–2.61 | 0.51 | |||
| Previous CABG | 1.18 | 0.41–3.42 | 0.76 | |||
| Laboratory data | ||||||
| Log NT-proBNP (per 1-unit increase) | 3.96 | 2.39–6.57 | <0.001 | 1.61 | 0.69–3.72 | 0.27 |
| eGFR (per 1-mL/min/1.73 m2 increase) | 1.00 | 0.99–1.11 | 0.76 | |||
| Hemoglobin (per 1-g/dL increase) | 0.85 | 0.70–1.03 | 0.092 | |||
| Albumin (per 1-g/dL increase) | 0.14 | 0.08–0.26 | <0.001 | 0.16 | 0.07–0.39 | <0.001 |
| Echocardiographic data | ||||||
| LVEF (per 1% increase) | 0.95 | 0.93–0.98 | <0.001 | 1.01 | 0.97–1.04 | 0.80 |
| Aortic valve area (per 1-cm2 increase) | 0.02 | 0.003–0.13 | <0.001 | 0.10 | 0.007–1.35 | 0.083 |
| AV mean pressure gradient (per 1-mmHg increase) | 1.00 | 0.99–1.02 | 0.99 | |||
| Moderate or greater MR | 3.19 | 0.15–8.83 | 0.025 | 1.19 | 0.30–4.74 | 0.81 |
| Procedural characteristics | ||||||
| First-generation THV | 1.06 | 0.54–2.00 | 0.85 | |||
| General anesthesia | 2.05 | 1.18–3.59 | 0.011 | 1.79 | 0.86–3.74 | 0.12 |
| Transfemoral approach | 0.50 | 0.22–1.11 | 0.088 | |||
| Device success | 0.36 | 0.12–1.10 | 0.073 | |||
| Procedural complications | ||||||
| Combined endpoint | 5.77 | 2.92–11.2 | <0.001 | |||
| Procedural stroke | 18.6 | 7.93–43.4 | <0.001 | 31.6 | 10.9–91.7 | <0.001 |
| Life-threatening bleeding | 2.21 | 0.48–10.2 | 0.31 | |||
| Acute kidney injury Stage 2 or 3 | 1.87 | 0.23–15.5 | 0.56 | |||
| Major vascular complication | 1.55 | 0.35–6.91 | 0.57 | |||
| Pacemaker implantation | 0.38 | 0.09–1.58 | 0.18 | |||
| Moderate or greater postprocedural AR | 4.50 | 1.58–12.9 | 0.005 | 3.16 | 0.71–14.0 | 0.13 |
CI, confidence interval; OR, odds ratio. Other abbreviations as in Table 1.