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. 2021 Feb 24;21(4):326. doi: 10.3892/ol.2021.12588

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Copyright: © Yao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — PPI network of the DEGs, and the expression levels of the hub genes in PDAC tissues and normal tissues. (A) The Cytoscape software was used to construct a DEG-based PPI network. Upregulated genes are marked in red, while downregulated genes are marked in blue. (B) BiNGO was used to construct the biological processes of the hub genes. The color depth of the nodes refer to the corrected P-value of ontologies, while the size of the nodes refer to the number of genes that are involved in the ontologies. (C) The Gene Expression Profiling Interactive Analysis database was used to analyze the differences in the expression levels the hub genes between PDAC tissues and normal pancreatic tissues. *P<0.05. PPI, protein-protein interaction; DEGs, differentially expressed genes; PDAC, pancreatic ductal adenocarcinoma.